There has been significant decline in the clinical condition of Kalaignar Dr M Karunanidhi over the last few hours, the latest bulletin from Kauvery Hospital said on Tuesday evening at 4.30pm. 

The bulletin said, "Despite maximum medical support, his vital organ functions continue to deteriorate. His condition is extremely critical and unstable."

The latest medical bulletin from Kauvery hospital came 24 hours after the previous update on Monday. The previous statement from the hospital had said that there was a decline in the health of the DMK president, and that the following 24 hours would be crucial for the prognosis.

The statement on Monday evening had also stated that maintaining Karunanidhi’s vital organ functions continues to remain a challenge considering his age and that he is on continuous monitoring.

On Tuesday, President of Tamil Manila Congress GK Vasan, Tamil Nadu Congress Committee President EVKS Elangovan and the Viduthalai Chiruthaigal Katchi (VCK) chief Thol Thirumavalavan visited the hospital and met MK Stalin to enquire about the Dravidian leader's health.

DMK President Karunanidhi was rushed to Kauvery Hospital following sudden decrease in his blood pressure late on July 26. Following the stabilisation of his blood pressure, he was admitted to the ICU for Urinary Tract Infection. His health has been fluctuating since then, with the hospital releasing seven health bulletins over the last ten days.